Helicure

Composition:

Each Heli-cure tablet contains:

* Omeprazole     20 mg

* Tinidazole        500 mg

* Clarithromycin  250 mg

 

Properties:

Helicure tablets contain breakthrough and carefully selected formula for the eradication of Helicobacter pylori organism, hence the management of both gastric and duodenal ulcers. Helicure with its unique combination of a long acting and specific antibiotic (Clarithormycin), an efficient proton pump inhibitor (Omeprazole) and a powerful antibacterial agent with activity against anaerobes (Tinidazole), plays a crucial role in the safe eradication of the Gram-ve anaerobic organism (Helicobacter pylori), which is per the recent studies is responsible for and associated with most of the upper gastrointestinal disorders e.g. gastric ulcer, duodenal ulcer, antral gastritis and gastric carcinoma, accordingly, eradication of H. Pylori leads to radical cure of peptic ulceration and lowers the incidence of recurrence.

 

Indications:

Eradication of H. Pylori in patients with peptic ulcers with the objective of reducing the recurrence of duodenal and gastric ulcers caused by this organism.

* Duodenal ulcer

* Gastric ulcer

* Moderate and severe reflux oesophagitis


Administration:

Unless otherwise prescribed by the physician. The usual dose of Helicure is 2 tablets / day (one in the morning and one in the evening) for two weeks preferably during meals.


Adverse Reactions:

All Heli-cure ingredients are usually well tolerated. However some minor reaction have been occasionally reported e.g. nausea, dyspepsia, diarrhea (or constipation), vomiting, flatulence, abdominal pain, stomatitis, glossitis, headache, skin rash, taste perversion may also occur. However most of these reactions are mild enough not to justify discontinuation of the treatment with Heli-cure. Reversible tongue discoloration has been seen in clinical trials when Clarithromycin and Omerprazole were given together.

 

Contraindications:

Heli-cure is contraindicated in patients with known hypersensitivity to any of its components.

 

Pregnancy and Lactation:

The safety of Heli-cure dring pregnancy and breast feeding of infants has been established. So, Heli-cure should not be used during pregnancy and lactation unless the benefit is considered to outweigh the risk.


Interactions with other medications:

Drug-drug interaction may occur between any of Heli-cure components and other drugs, such as: warfarin, Diazepam, Terfenadine, Phenytoin, Ergot alkaloids, Lovastatin, Cyclosporin, Theophylin and Cisapride, so it is advisable not to concomitantly administered Heli-cure with any of the mentioned medicaments and take into consideration that Omeprazole increases serum level of Clarithromycin

 

Special Warnings & Precautions:

One of Heli-cure components (Clarithromycin) is principally excreted by liver and kidneys. Caution should be exercised in administrating Heli-cure to patients with impaired hepatic or renal function, However, dosage adjustments are not usually required except in patients with severe impairment.


Overdose:

There is no available studies on the effect of Heli-cure overdosage in man. However, treatment of overdosage is symptomatic and supportive. Gastric lavage may be useful.


How Supplied:

Pack of 14 tablets(7 blisters, 2 tablet in each)

Store below 30oC, protect from light. Keep out of the reach of children.